Yes, I’ve got USB Serial for Core, Photon and Electron connected to Windows 10.
Once you find the device under “Other Devices” or “Ports” in DevMgr, you’ll need to update drivers by selecting driver (as shown in the docs)
https://docs.particle.io/guide/getting-started/connect/photon/#using-windows
Using these drivers
https://s3.amazonaws.com/spark-website/Particle.zip