Well, if you want to unsolder the MFF2 SMD SIM and replace it, it would probably work, but it would be very difficult to do at scale, and it would obviously void the warranty.
It technically is possible to enable the use of a 4FF SIM card on a custom base board, but it involves moving three 201 resistors on the SoM itself. This too is difficult to do at scale and also voids the warranty.
Also in the growth tier the price is the same for using the Particle SIM card as for a 3rd-party SIM card.