Yes, you can send multiple data values in a Particle publish if you format the event data as JSON. Say you want to send 2 integers, a and b, and a string c. You might send up something like this in the event data.
{"a":12,"b":34,"c":"testing"}
Then, instead of using {{PARTICLE_EVENT_VALUE}}
you can use {{a}}
or {{b}}
or {{c}}
in your webhook definition. It works in url, query parameters, JSON post data, and form post data.
There are even more complicated scenarios using nested object and arrays, but just that much is quite powerful.
My tutorial: